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The Poison needle (formerly Poison knife) is a weapon in the Dragon Quest game series. It is a novelty weapon that has a 1/8th chance to instantly kill an enemy in a single strike, but otherwise can only inflict one point of damage. Both of these attributes make the needle an invaluable weapon against metal slimes.
The Poison Needle is a weapon with no bonus attack and will always do 1 damage. However, it can randomly kill a non-boss enemy. The needle can only be held by Jessica and is required for various alchemy recipes. It can be bought for 1900g and sells for 1000g.